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The Invisible Guardians Behind Chikungunya Fever Testing

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Chikungunya Fever

Recently, Chikungunya fever – a mosquito-borne viral disease characterized by high fever and severe joint pain – has emerged in some parts of China, causing many to fear mosquito bites!
The daily epidemic reports and test results seen by the public are supported by a rigorous and highly efficient public health testing system. Today, we reveal the key forces silently enabling “precise traceability” and “rapid diagnosis” behind these tests.

01 Understanding Chikungunya Fever

Preventing mosquito bites is the best medicine!

02 Rapid Detection & Precise Tracing

The “Keen Eyes” of Epidemic Control
For complex, rapidly spreading viruses like chikungunya, clinical symptoms alone are insufficient for accurate diagnosis. To enable early detection, diagnosis, and isolation, disease control systems rely on advanced lab technologies that act as “keen eyes”—quickly identifying the virus, tracing infection sources, and guiding targeted responses.

The Chikungunya Diagnosis and Treatment Guidelines (2025 Edition)issued by China’s National Health Commission mandates the following ​gold-standard lab tests:

Nucleic Acid Testing
Real-time PCR, isothermal amplification

Virus Isolation
Sensitive cell lines (Vero, C6/36, BHK-21)

Serological Testing
ELISA, immunochromatography

These detection methods rely on highly automated and precision liquid-handling technologies, with peristaltic pumps serving as the “unseen driving core” for multiple critical processes.

03 The “Invisible Guardian” in the Lab

Three Critical Roles of Peristaltic Pumps

  1. Safety Barrier: Contamination-Free Operation

When handling potentially infectious samples, peristaltic pumps utilize contact-free fluid transfer—liquids flow solely within disposable tubing, completely isolated from pump mechanics.

Key Advantages:​​

  • Eliminates cross-contamination risksbetween samples
  • Providesextra protection for lab personnel

Typical Application: 

In fully automated nucleic acid extraction workstations, peristaltic pumps drive reagents (lysis buffers, wash solutions, and elution buffers) to interact with magnetic bead systems, enabling high-efficiency nucleic acid extraction and purification. Throughout the process, liquids only contact tubing and consumables, effectively preventing cross-contamination.​

【Lead Fluid Product Recommendation】​

  • Flow rate ≤190 mL/min
  • Analog control for easy integration
  • Corrosion-resistant engineering plastic pump head with service life ≥1500h
  • Compact structure, suitable for ODM applications
  • Transparent pump cover for easy maintenance

2. Precision Dispensing: Highly Consistent and Stable Output

In public health testing, whether for molecular diagnostics (e.g., PCR/qPCR) or immunoassays (e.g., immunochromatographic test strips), the stability of liquid dispensing during reagent production directly determines the reproducibility and reliability of test results. Even microliter (μL)-level variations can impact final interpretations.
The advantage of peristaltic pumps lies in their ability to maintain minimal dispensing errors during high-throughput operations, ensuring batch-to-batch reagent consistency.

Typical Scenario 1: Molecular Diagnostics​

On reagent production lines for molecular testing, peristaltic pumps enable contamination-free, large-scale precision filling.

【Lead Fluid Product Recommendation】

  • Filling Range: 0.01–9999.99 mL
  • Filling Accuracy: ±1%
  • Compliance: GMP & 21 CFR Part 11
  • USB Import/Export Recipes: Supports custom naming (including Chinese characters)
  • Modular Channel Design: Expandable up to 32 channels
  • Online Fine-Tuning: Real-time adjustment of filling errors without stopping production

Typical Scenario 2

In the manufacturing of immunochromatographic test strips (e.g., COVID-19 antigen test cards), industrial syringe pumps are used to precisely and uniformly dispense gold-labeled antibodies and other reagents onto specific locations of conjugate pads and membrane materials. This directly impacts:

  • Test sensitivity(detection capability)
  • Batch-to-batch consistency

【Lead Fluid Product Recommendation】

3. Gentle Fluid Handling: Preserving Viral and Cellular Viability

Virus culture and sequencing preparations often require prolonged, continuous perfusion of fresh culture media. The low-shear and pulsation-free delivery of peristaltic pumps helps maintain the integrity of both cells and viruses, ensuring higher-quality samples for downstream analysis.

Typical Scenario​

In virus isolation bioreactors, peristaltic pumps continuously supply nutrients to cells, supporting stable viral propagation.

【Lead Fluid Product Recommendation】

  • Continuous operation flow rate ≤370 mL/min
  • Intermittent operation flow rate ≤550 mL/min
  • Low-pulsation output with high stability
  • Flip-top tubing loading design for one-handed operation
  • Spring-loaded compression mechanism extends tubing life
  • Compact structure compatible with multiple tubing specifications4.

4. Lead Fluid

Delivering “Steady Power” to Public Health Testing

Lead Fluid Technology specializes in precision fluid transfer, committed to delivering accurate, safe, and stable fluid handling solutions for laboratory automation, molecular diagnostics, cell culture, and other applications.

Against chikungunya, every one of us is the first line of defense—implement thorough mosquito control! At the same time, trust in the public health system’s rapid response and precision testing capabilities. In laboratories, countless scientists and their “precision partners” work day and night, safeguarding public health through technological power!