With the improvement of living standards and the continuous growth of demand for healthcare, the pharmaceutical industry has maintained a rapid development rate. In order to ensure the efficacy and safety of drugs, the demand for high-quality solutions is also increasing.
Damping and oxidation are the two main factors leading to product degradation. Drug coating is the most important and cutting-edge technology in modern pharmaceuticals, which can effectively alleviate this problem.
1.What is pharmaceutical coating?
Pharmaceutical coating refers to the coating of sugar or other film-forming materials on the outer surface of a solid pharmaceutical formulation in a specific device using a specific process, allowing it to dry and become a layer or layers of multifunctional protective layers with different thicknesses and elasticity that are tightly adhered to the surface. Coating can improve drug stability, isolate incompatible ingredients, improve recognition, mask adverse odors, reduce drug irritation, delay and control drug release, improve drug appearance, and enhance appetite.
2.The peristaltic pump assisted pharmaceutical coating process.
The coating machine mainly sprays the coating liquid into the rotating material through atomization, and the heating system allows the coating liquid to quickly dry after contact with the material surface and adhere to it to form a film coating.
In order to make the surface of the coated drug fine and smooth, with uniform color and particle size, a peristaltic pump is needed to transport the coating solution during the coating process.
The core of the film is in a clean and closed rotating drum of the coating machine, constantly undergoing complex trajectory movements, flipping smoothly and exchanging frequently. The coating liquid is transported by a peristaltic pump and sprayed onto the core from an imported spray gun.
At the same time, the filtered hot air is introduced by the air duct distributor in the center of the drum, and passes through the core through a fan-shaped fan. Under the action of exhaust and negative pressure, it is extracted from the air duct on the other side and discharged after dust removal, allowing the coating medium to quickly dry on the surface of the core, forming a strong, dense, and smooth surface film.
3.Uncover the secret behind choosing peristaltic pumps
The coating machine requires the delivery pump to be easy to clean, meet high hygiene requirements, avoid dead corners, prevent the accumulation or blockage of suspended coating liquid, and ensure stable flow rate to ensure uniform droplet size after atomization.
BT600S Speed Variable Peristaltic Pump
The Lead Fluid peristaltic pump can highly match the needs of the coating machine, and the peristaltic pump has various advantages.
* High hygiene level, easy to clean: Due to its structure, the material conveyed by the peristaltic pump will only come into contact with the inner wall of the hose, which can prevent the pump body from polluting liquid materials. There are no dead corners on the pipeline, making cleaning, disinfection, and sterilization extremely simple.
* Low maintenance cost, avoiding dead corners: The peristaltic pump has no valves and seals, eliminating various maintenance troubles. It has good self sealing performance and can effectively avoid dead corners.
* Low shear force, more suitable for pharmaceuticals: peristaltic pumps have low shear force, making them an ideal tool for conveying shear sensitivity. It can transport liquid materials and macromolecular materials containing solid particles without changing the state of the material.
* Stable and adjustable flow rate: The peristaltic pump has stable flow rate and can transmit liquid materials with stable flow rate. And the flow rate range is wide and can be continuously adjusted, providing different flow rates as the process requirements change.
The Lead Fluid peristaltic pump effectively improves the working efficiency of the coating machine and ensures the stability of the drug coating. In the future, Lead Fluid will continue to introduce more high-quality products made in China, and work together with industry colleagues to continue promoting the development of China’s pharmaceutical industry.